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A Digital Squamous Cell Carcinoma Mimicking a Diabetic Foot Ulcer, With Early Inguinal Metastasis and Cancer-Related Lymphedema.

Identifieur interne : 001537 ( Main/Exploration ); précédent : 001536; suivant : 001538

A Digital Squamous Cell Carcinoma Mimicking a Diabetic Foot Ulcer, With Early Inguinal Metastasis and Cancer-Related Lymphedema.

Auteurs : Hyun Chul Park [Corée du Sud] ; Hyoung Il Kwon ; Hyun Woo Kim ; Jeong Eun Kim ; Young Suck Ro ; Joo Yeon Ko

Source :

RBID : pubmed:26825165

Descripteurs français

English descriptors

Abstract

Although squamous cell carcinoma (SCC) is the second most common nonmelanoma skin cancer, clinicians have difficulty diagnosing SCC of the toe because its clinical features can mimic other less serious diseases. Clinicians are especially prone to misdiagnose SCC of the toe as diabetic foot ulcer in patients with diabetes mellitus because of the clinical similarity of the 2 ailments. SCC of the toe is generally considered to have a low risk of metastasis. Locoregional or distant metastases without bone or tendon involvement are particularly rare. The authors report here an interesting case of rapidly spreading SCC of the toe with metastasis to multiple lymph nodes and cancer-related lymphedema. Physicians should be aware of the possibility of malignancy when they encounter chronic and recalcitrant ulcerative lesions of the digits.

DOI: 10.1097/DAD.0000000000000412
PubMed: 26825165


Affiliations:


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Le document en format XML

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<nlm:affiliation>Department of Dermatology, Hanyang University Hospital, College of Medicine, Hanyang University, Seoul, Korea.</nlm:affiliation>
<country xml:lang="fr">Corée du Sud</country>
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<title level="j">The American Journal of dermatopathology</title>
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<term>Biopsy</term>
<term>Carcinoma, Squamous Cell (chemistry)</term>
<term>Carcinoma, Squamous Cell (complications)</term>
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<term>Carcinoma, Squamous Cell (secondary)</term>
<term>Cisplatin (administration & dosage)</term>
<term>Diabetic Foot (diagnosis)</term>
<term>Diabetic Foot (pathology)</term>
<term>Diagnostic Errors</term>
<term>Fatal Outcome</term>
<term>Fluorouracil (administration & dosage)</term>
<term>Humans</term>
<term>Immunohistochemistry</term>
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<term>Lymphedema (etiology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Positron-Emission Tomography</term>
<term>Predictive Value of Tests</term>
<term>Skin Neoplasms (chemistry)</term>
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<term>Skin Neoplasms (diagnosis)</term>
<term>Skin Neoplasms (drug therapy)</term>
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<term>Toes (pathology)</term>
<term>Treatment Outcome</term>
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<term>Carcinome épidermoïde (traitement médicamenteux)</term>
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<term>Facteurs temps</term>
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<front>
<div type="abstract" xml:lang="en">Although squamous cell carcinoma (SCC) is the second most common nonmelanoma skin cancer, clinicians have difficulty diagnosing SCC of the toe because its clinical features can mimic other less serious diseases. Clinicians are especially prone to misdiagnose SCC of the toe as diabetic foot ulcer in patients with diabetes mellitus because of the clinical similarity of the 2 ailments. SCC of the toe is generally considered to have a low risk of metastasis. Locoregional or distant metastases without bone or tendon involvement are particularly rare. The authors report here an interesting case of rapidly spreading SCC of the toe with metastasis to multiple lymph nodes and cancer-related lymphedema. Physicians should be aware of the possibility of malignancy when they encounter chronic and recalcitrant ulcerative lesions of the digits.</div>
</front>
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